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What is the Cas9 protein that is often mentioned in news?

  1. A molecular scissors used in targeted gene editing
  2. A biosensor used in the accurate detection of pathogens in patients
  3. A gene that makes plants pest-resistant
  4. A herbicidal substance synthesized in genetically modified crops

Explanation

Option (a) is correct
  • Cas9 is a protein associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system, which is a technology for gene editing. It acts as a pair of “molecular scissors” that can precisely cut DNA at specific locations. CRISPR-Cas9 is a technology that allows the modification, addition, or removal of specific DNA sequences, changing genome portions.

Diagram illustrating CRISPR-Cas9 gene editing process, showing Cas9 enzyme guided by RNA to cut DNA at a specific target site, followed by DNA repair with inserted sections. Key components, applications across medical, research, agriculture, conservation, industrial, and animal biotechnology fields, along with advantages like precision and cost-effectiveness, and disadvantages such as off-target cuts and ethical issues, are highlighted with color-coded sections and labeled arrows.

Answer: (a) A molecular scissors used in targeted gene editing; Difficulty Level: Easy
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